Custom Versatile 4x12 speaker pairings

Well I looked in the search bar, and saw things kind of close to what i was looking for, but I couldn't directly answer my question. Well 1st of all i have a an open back pine cab that has a mix of 2x12's (Eminence GB legends) and 2x10's (Eminence Ragin Cajuns) in a 4x10 size cab 8 OHM mono. I plan on using this cab in conjunction with a new custom Aftershock 4x12 closed back cab (Orange 4x12 size specs). I play many styles of music. Hendrix, Zeppelin, Van Halen, Lynch Mob, GNR, Pearl Jam, SRV, Fingerstyle electric, classical, originals etc, etc.

I play a Suhr Pro Modern Mahogany, H-S-H with a blower switch, also i play a Warmoth S-S-S strat. Well I have a FJA Mods JFD 100. Which is a 100 watt all tube SIR modded Marshall style head. Think Slash Appetite for destruction, George Lynch gain channel. That can do Slipknot as well. Also a Plexi clean channel, think stock 68 Super Lead that can do early EVH.

So i was looking for speaker recommendations for the custom 4x12 Orange cab size specs. I like the idea of mixing speakers. I have owned a single Retro 30 in a JCM 800 combo. So i know it's a good speaker. I also like the way the Invaders, and several others sound. What would be a good combo of speakers for max versatility and tones? Between vintage and modern, clean and distorted, dynamic and complimenting of each other that cleans up with a guitars volume knob, and gets varying levels of hair and bite?. That could also, be used seperately as a stand alone closed back 4x12 at 8 OHM mono without blowing a speaker, on a cranked 100 watt EL-34 powered modded Marshall style amp? Also would you recommend X pattern combo's of speakers, side by side, or top and bottom? Like 2 of the same in which configuration?

Thank you so much,

Marcus